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Should you still administer the B12 injection

This is especially seen in muscle tissue, which TB-500 has been shown to help heal in animal studies

Retatrutide Titration Protocols Retatrutide follows a similar gradual escalation pattern, though the dose increments differ [14]: Typical Retatrutide Escalation: Weeks 1-4: 2 mg weekly Weeks 5-8: 4 mg weekly (first studied therapeutic dose) Weeks 9-12: 6-8 mg weekly (intermediate range) Weeks 13-16: 8-12 mg weekly (maximum studied doses) Week 17+: Maintenance at target dose The longer titration period (16 weeks to reach maximum dose) helps mitigate the significant gastrointestinal effects associated with retatrutide's multi-receptor activation

Your doctor will typically monitor your response through clinical improvement and blood tests such as full blood count, rather than rechecking B12 levels after starting injections

PubMed Wadden, T.A., Chao, A.M., Machineni, S., Kushner, R.F., Ard, J., Srivastava, G., et al