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A randomized, double-blinded, placebo-controlled trial published in the European Journal of Nutrition found that oral glutathione at 1,000 mg per day increased blood glutathione levels by 30 to 35% in erythrocytes, plasma, and lymphocytes after 6 months of consistent supplementation

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(2) Another randomised, double-blind, placebo-controlled, parallel, three-arm study conducted with 60 volunteers showed glutathione effectively influenced skin properties such as reducing skin pigmentation and improving elasticity (3)