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Semaglutide 2.4 mg once weekly, a subcutaneously administered GLP-1 RA approved for obesity treatment in 2021, results in 1517% mean weight loss (WL) with evidence of cardioprotection

Am J Physiol Endocrinol Metab 310:E947E957 Dai Y, Mehta JL, Chen M (2013) Glucagon-like peptide-1 receptor agonist li- raglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation

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