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It should be noted, however, that resistance and HR (programmed cell death) do not necessarily correlate (Bendahmane et al., 2016)

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The numbers for each group are between 3 and 5 due to very laborious effort during exposure to cigarette smoke as well as the analysis of cardiac dysfunction using echocardiography each week for all the animals

198,199 GRP78 (HSP70) contributes to 5-FU resistance in colorectal and ovarian cancer cells by modulating the PI3K/AKT/mTOR and c-Src/LSF/TS signaling pathways