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They share precursor biology but engage distinct receptors (GLP1R for GLP-1, GLP2R for GLP-2) with different downstream effects
In type I diabetes, destruction of pancreatic -cells leads to loss secretion of insulin, while the major problem in type II diabetes is insulin resistance of peripheral tissues
Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice (2019) Researchers took gut microbes from a human with autism and placed them in mice and the mice developed autism
Erythrocytes can also develop OS due to exogenous ROS that are able to diffuse and cross the RBC membrane
Athletes using GLP-1s will need to closely watch their diet and training to make sure they maintain muscle (perhaps while dealing with the vomiting, nausea, and diarrhea often associated with GLP-1s)
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