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However, lifestyle-based weight loss strategies are not effective in the long term

EClinicalMedicine 3(72):102624 Jensen SBK, Srensen V, Sandsdal RM, Lehmann EW, Lundgren JR, Juhl CR et al (2024) Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial

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Blood cells sticking together is what leads to a blood clot which can cause a stroke.

Studies report improvements in insulin resistance, measured by HOMA-IR, along with reductions in basal insulin levels