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High uptake of [211C]acetyl-L-carnitine into the brain: a PET study

This is more commonly associated with oral supplementation at higher doses but can theoretically occur with any route of administration

In randomised trials, NAC has improved ovulation rates significantly more than placebo and has been a useful adjuvant when added to clomiphene or letrozole, particularly if you haven't responded to ovulation-induction medication alone

Bottom line: Human RCT evidence is emerging (positive MRI/cognition signals with liraglutide in Phase 2b)

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