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3 The lead investigator's own counsel was cautious, especially for people already at elevated risk of clotting

This is particularly interesting as next-generation multi-receptor agonists that incorporate glucagon receptor agonism have shown tremendous promise for weight loss and glycemic control, including triagonists for the GLP-1R, GIPR and GCGR 44,45

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Semaglutide is a viscous solution, meaning it is thicker and denser than water, so it sits as a distinct pocket under your skin for several hours before your body gradually absorbs it into the bloodstream