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PMC 7657338

Ipamorelin is called the first truly selective growth hormone secretagogue because it stimulates GH release without measurably raising cortisol, prolactin, or ACTH at therapeutic doses

Dose it preventively, use a bioavailable form, and recognize it as one tool in a broader strategy that includes hydration, pacing alcohol intake, and eating before drinking

Second, the patient should meet established criteria for pharmacologic weight management intervention, such as BMI 30 kg/m or BMI 27 kg/m with weight-related comorbidities, consistent with FDA indications

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