In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]
many patients begin with a short series of injections spaced over weeks, then shift to a maintenance schedule that holds the gains
A serum can fade existing pigment and interrupt new pigment production, but it cannot block the UV, visible light, and heat that keep melasma coming back
There's a seal on the bottle cap and inside once you open it
In November, the company reached a deal with the Trump administration to offer the lowest dose for $149 per month for people paying out of pocket, in exchange for tariff relief