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Studies have shown that APC transporter proteins play a role in protecting tumor cells by actively transporting intracellular toxic substances or drugs to the extracellular compartment, thereby contributing to chemoresistance (70,71)

A study on one compound does not prove a two- or three-compound stack

Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation

doi: 10.1016/j.tplants.2018.06.004 64 Rodriguez-PeaR.MounadiK