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Gandhi GY (2021)
HCl is the form used in nearly all the cited trials and is roughly 87% arginine by weight, so each capsule delivers about 870 mg of actual arginine
J Thorac Cardiovasc Surg 161(4):1363-1364, 2021
Last week, the FDA updated its drug shortage database, marking the shortage of Eli Lillys Zepbound as resolved
A supervised trial of berberine and semaglutide is generally not a good idea if you: Have a history of severe hypoglycemia Have advanced liver or kidney disease Are pregnant, planning pregnancy, or breastfeeding Have complex polypharmacy (multiple meds that rely on CYP3A4/CYP2D6) Have a history of pancreatitis or serious GI motility disorders (which already restrict semaglutide use) If any of these apply, talk with your clinician about safer alternatives
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