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In the self-controlled case series design, we used Poisson regression to estimate suicide or suicide attempts across study periods, calculating incidence rate ratio (IRR) with 95% confidence intervals using the pretreatment period as reference

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Retatrutide differs from other weight loss medicines partly because the glucagon receptor it activates is thought to increase energy expenditure and promote fat burning in addition to the appetite-suppressing effects of GLP-1 and GIP

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This helps your body adjust and reduces side effects