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GLP-1RAs may be the drugs of choice for the treatment of diabetes because of their cardioprotective, neuroprotective and renal protective activities other than lowering blood glucose, while not causing side effects of hypoglycemia and weight gain, with a proven efficacy and safety (Sharma et al., 2018
July 2019
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In England , the National Institute of Health and Care Excellence (NICE) has approved three GLP-1 class medications for weight management in adults, to be used alongside a reduced calorie diet and increased physical activity: Liraglutide Semaglutide Tirzepatide The two most recently approved are semaglutide (available as Wegovy) and tirzepatide (available as Mounjaro/Zepbound)
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