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106 In 2017, Tanzeum was removed from the preferred drug list of leading pharmacy benefit manager (PBM) company Express Scripts and was replaced by Eli Lillys Trulicity, highlighting Tanzeums weak market presence

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10.1016/j.jep.2019.112277 122 YamazakiK.FukudaK.MatsukawaM.HaraF.MatsushitaT.YamamotoN.et al (2003)

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The primary focus was to assess changes in QTc intervals, a measure of cardiac electrical activity, to determine any potential risks associated with doxepin use