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Some individuals might only need injections once or twice a year
Additionally, a 10-week study in overweight or obese post-menopausal women with prediabetes found that 250 mg NMN per day partially increased muscle insulin signaling and sensitivity, but no change in mitochondrial oxidative capacity was found 324
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However, the predominance of rodent studies raises questions about translatability to human pathophysiology and therapeutic responses
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