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However, because these breath tests are neither sensitive nor specific (up to 60% false negatives), most Functional doctors will treat a patient when they exhibit classic symptoms

This suggests that IL-8 may play a critical role in the early response to immunogenic and inflammatory signals with its response to nonspecific stimuli 38

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This binding initiated biological responses, inhibition, or amplification of transmembrane signal transduction pathways ( + lymphocytes, play a crucial role in macrophage activation, differentiation, and induction of proinflammatory expression such as iNOS (Sol et al., 2021)

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