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Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect

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We therefore suggest for future studies on monothiol mechanism (i) to take the bulkiness of the putative Grx(SSR) intermediate, an S N 2 reaction geometry, and a possible accumulation of Grx(SSR) as an artifact into account (Fig

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