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Be sure to contact your primary care doctor or endocrinologist immediately if you notice any of the following: Allergic reactions: rash, swelling, or hives Heart palpitations: fluttering or rapid heartbeat Vision problems: sudden changes or blurriness Signs of dehydration: extreme thirst, dry mouth, dizziness, or dark-colored urine Gallbladder issues: intense stomach pain, nausea, or fever Kidney problems: decreased urine output or swelling in your legs and ankles Pancreatitis: severe abdominal pain that may radiate to your back, fever, or persistent nausea Possible thyroid cancer symptoms: a lump in your neck, hoarseness, difficulty swallowing, or breathing problems
All the outcomes were analyzed with the use of a Cox proportional-hazards model with randomized group assignment as a categorical fixed factor
Osman AT, Sharkawi SMZ, Hassan MIA, Abo-youssef AM, Hemeida RAM (2021) Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats
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It also independently stimulates growth factors through the wound-healing response
