JCI Insight 3 , e122011 (2018)
Mechanism: Acts as a signal peptide that modulates fibroblast activity, collagen and glycosaminoglycan synthesis, antioxidant signaling, and copper bioavailability [1][2]
Human growth hormone (HGH), produced by the anterior pituitary gland, plays a central role in: Body composition: GH promotes fat breakdown (lipolysis) and supports lean muscle preservation Tissue repair: GH stimulates collagen synthesis, wound healing, and cellular regeneration Sleep quality: GH is primarily released during deep (slow-wave) sleep Bone density: GH works alongside IGF-1 to maintain bone mineral density Immune function: GH supports immune cell proliferation and activity Cognitive function: GH receptors are present throughout the brain Growth hormone production declines approximately 14% per decade after age 30, a process sometimes called somatopause
An option and weve done the studies and itll be indicated within our label is you can switch to an oral form
However, chronic exposure can promote stable increases in these metabolic phenotypes, as evidenced by our resistant organoid models (Extended Data Fig