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Key Strengths: Key Weaknesses: Ideal Patient Profile: Patients who refuse or can't tolerate injections
doi:10.1177/1933719119828099
Nusinersen: first global approval
Weeks 5 through 8: the 0.5 mg phase Week five marks the first dose escalation
When THR- is stimulated by an agonist (e.g., resmetirom), it improves liver health by initiating a cascade of processes that are often dysregulated in patients with MASH and that are associated with disease progression and the development of hepatic fibrosis
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