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Furthermore, spiculations appear in eryptotic cells, resulting in the loss of their biconcave shape [85]
Chem Biol Interactx 366:110137 Li R, Xie L, Li L, Chen X, Yao T, Tian Y et al (2022b) The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice
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Notably, histological analysis at this time point revealed no significant hepatocyte damage, suggesting that the rapid decrease in hepsin protein levels may primarily result from the activation and subsequent degradation of the hepsin serine protease in response to APAP-induced hepatotoxicity
