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Interestingly, the aryl hydrocarbon receptor (AhR) of the tryptophan-kynurenine pathway serves as a critically important mediator between tryptophan metabolism, immune reactions, and tissue homeostasis (4143), and several kynurenine metabolites have been associated with fatigue (44, 45)
Gugliandolo, E
BMJ Medicine, 5(1), e002150
In topical applications, you are recommended to use the cream or other substance once a day
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