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Glycine tomentella hayata extract and its ingredient daidzin ameliorate cyclophosphamide-induced hemorrhagic cystitis and oxidative stress through the action of antioxidation, anti-fibrosis, and anti-inflammation
In addition to pathogenic role, KCs also contribute to protection against AILI by producing some hepato-regulatory cytokines and mediators, including IL-6, IL-10, IL-18 binding protein and complement 1q (C1q) [42]
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Mechanistically, lichen secondary metabolites may contribute through membrane effects and interference with urease/biofilm-associated pathways, which aligns with the observed urease decrease and partial biofilm reduction
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