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6 M rabbit GAPDH (Sigma-Aldrich) was incubated for 20 min in a total volume of 500 l of 100 mM Tris/HCl p H 8.0, 1 mM EDTA, 1.4 mM H 2 O 2 and 3 mM GSH, which led to glutathionylation and inactivation of enzymatic activity

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Pathogenic variants in the SCNN1B and SCNN1G genes are the causes of Liddle syndrome with pathogenic variants in the SCNN1B gene being identified in the individuals in the original pedigree of Liddle syndrome

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