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JAMA Ophthalmol
This can reduce methylation, contributing to a wide range of MTHFR gene symptoms
The mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving blood flow, and modulation of dopamine and serotonin systems
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A partir de los 4550 aos, la funcin mitocondrial declina en msculo y cerebro simultneamente, la sntesis endgena de carnitina disminuye y los niveles de acetilcolina colinrgica comienzan a caer
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