We included prospective studies and randomized clinical trials (RCTs) published in English or Spanish
Approaches include enteric coatings that protect peptides from stomach acid, permeation enhancers that help peptides cross the intestinal wall, and nanoparticle encapsulation systems
YX: Writingoriginal draft, Data curation, Conceptualization
Cure SMA and Cure SMA Canada funded the study for the North American sites, while Bild Ein Herz fr Kinder funded the German site
This prolongs incretin activity, increases postprandial insulin secretion from pancreatic beta cells, decreases glucagon secretion, delays gastric emptying, and lowers blood glucose levels (National Center for Biotechnology Information, 2023a)