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A potential future avenue includes long-acting analogues of LEAP2, a native antagonist of the ghrelin receptor, which may reduce food intake by attenuating ghrelin-mediated orexigenic and lipogenic signaling
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This metabolic rewiring suggests that the Warburg effect and ferroptosis evasion may be mechanistically linked, representing complementary adaptive strategies that collectively support malignant transformation and tumor progression
Waltham, MA: Elsevier/AP
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