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Serious risks like allergic reactions or kidney stress can occur with unsupervised or high-dose treatments
Recently, intranasal administration of drugs has gained increasing interest as it can bypass the bloodbrain barrier
The pathogenesis can be explained by the fact that the number of circulating invariant natural killer T cells (iNKTs), a subset of innate T cells, is lower in individuals with diseases characterized by autoreactive tissue inflammation, such as psoriasis
In the absence of coenzyme B12, tetrahydrofolate cannot be regenerated from its inactive storage form, 5-methyl tetrahydrofolate, resulting in functional folate deficiency
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