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But endogenous antioxidants can redox cycle
doi:10.1080/15563650.2018.1538518
They were excluded if they had active major depressive disorder within 2 years prior to screening (or other severe psychiatric disorders such as schizophrenia or bipolar disorder) or a Patient Health Questionnaire-9 score of 15 or higher (indicating moderately severe or severe depression), or suicide ideation (type 4 or 5 on the Columbia Suicide Severity Rating Scale) or suicide behavior, within 30 days of screening
The incidence increased with higher doses, ranging from 5 mg (13%) to 15 mg (17%) weekly
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