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The SURPASS-J-combo trial embraced diabetic adults with HbA 1c 7% to 11% and BMI 23 kg/m 2 , stable weight and uncontrolled with therapy of metformin, thiazolidinedione, sulfonylureas, meglitinide, alpha-glucosidase inhibitor or SGLT2-i (81)
Segn ha informado la compaa, en SURMOUNT-MAINTAIN , tanto la dosis mxima tolerada (DMT) de tirzepatida como la mnima de 5 mg alcanzaron los objetivos primarios y todos los objetivos clave secundarios , demostrando que es posible el mantenimiento de la prdida de peso despus de 60 semanas de tratamiento inicial con tirzepatida DMT
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