First isolated as an effective diabetes drug, this insulin-boosting medication is also available to patients who need to lose a significant amount of weight in a consistent way and achieve long-term weight loss
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Furthermore, its tolerability profile, which includes weight gain, edema/fluid retention, fractures, and (rarely) bladder cancer in long-term use, could hinder its potential repositioning for depression [173]
Self-administered via weekly subcutaneous injection, they function by increasing hormones known as 'incretins', which stimulate the secretion of insulin from the pancreas, regulating blood glucose levels
When the moderator asked the experts to describe an ideal patient for combined therapy, each group of specialists reached a different conclusion