In clinical trials of SGLT2 inhibitors in type 2 diabetes, discontinuation rates among those receiving active treatment have been less variable, ranging from 21% during a median follow-up time of 50 months in the DECLARE-TIMI 58 trial of dapagliflozin to 29% during a mean follow-up time of 43 months in the CANVAS trial of canagliflozin [14,15,16,17,18]
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Research in this category explores coordinated peptide signaling across multiple pathways, enabling structured investigation of cellular communication systems and integrated signaling dynamics under controlled laboratory conditions