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This group only suggests such treatment when IGF-1 deficiency prevails, acting merely as a substitutive therapy, and never to exploit its multiple actions

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This assay was applied to both cultured cells and frozen tissue sections, with tissue sections counterstained with Nuclear Fast Red for better visualization

For the final stage of maturation into functional hepatocyte-like cells (HLCs), the proliferative HBs were cultured in hepatoZYME-SFM medium supplemented with 1X GlutaMAX