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Pretreatment with a Src inhibitor abolished these effects in HUVEC culture, placing Src upstream of the caveolin-1-eNOS step in the proposed cascade

Nutrients, 10 (11), 1738

One area that has attracted academic discussion, press coverage, and significant biotechnology/pharma R&D investment is concern about undesirable, collateral skeletal muscle mass (SMM) loss, and presumably by extension, loss of strength and function in people taking GLP-1 medications