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Vibration controlled transient elastography (VCTE) is most commonly used methods to assess for fibrosis, with liver stiffness measurements less than 8 kPa used to rule out advanced fibrosis
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Another strength is that the in vitro albumin binding studies were conducted at a molar ratio of approximately 10:1 for icodec versus semaglutide, closely resembling the icodec/semaglutide molar ratio in the IcoSema formulation, allowing for comparisons with the clinical situation
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