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SteckelbroeckSNassenAUgeleBLudwigMWatzkaMReissingerAet al
trial data describe these events as predominantly mild to moderate and tending to ease after titration (Lau et al., 2021)
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Specialized toxicology research shows no embryo-fetal developmental toxicity, no genetic mutagenicity in bacterial and mammalian cell assays, and no adverse reproductive effects in animal models
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