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EMT is observed in the process of renal interstitial, pulmonary and liver fibrosis [56,57,58,59], as well as in specific ocular tissue [32]
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Interestingly, metabolite analysis revealed decreased expression of acetyl-CoA, an essential precursor for lipogenesis, and downstream acetyl-CoA metabolites (Fig
Cell Rep (2018) 23(6):175466
This will result in an observed melting range that is artificially high and broad, potentially leading you to misinterpret a pure sample as impure
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