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Medications lose their effectiveness over time, and expired medication may not work as intended
When the Mann Whitney U statistic is considered the significantly highest were those which recorded a zero, that included high titres of HMGB1, total cholesterol, NF-kB, and the collagens I and III ( Table 1 ) in the DCM group
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However, patients with pre-existing glutathione deficiency, malnutrition, liver compromise, or genetic variations affecting detoxification enzymes may experience greater depletion impact and warrant more cautious use or provider oversight
