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Collectively, GLP-1-RAs are involved in the regulation of DNP mainly through the suppression of matrix remodeling, inflammation, oxidative stress, and mitochondrial dysfunction, as well as the improvement of neural structure and function [90,91,92,93] (Fig
It is well known that activation of efferent renal nerves exhibits the anti-diuretic effect by increased renin secretion, sodium reabsorption and renal vascular resistance [37, 38]
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