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Definitions Adjunct therapy - a treatment or therapy used in addition to another, not alone
Patients switching from Wegovy who had chronic constipation often report improvement on Zepbound
Is the patient using the lowest effective dose
Ahrn B (2019) DPP-4 inhibition and the path to clinical proof
In the withdrawal trial, participants switched to placebo regained about 14% over the following year. Tapering, at least 1.2 g/kg of protein, resistance training, and follow-up reduce the risk, but no post-stop protocol guarantees maintenance
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