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the AA sequence similarity from microorganisms to mammals ranges from 43% to 98%

This can slow metabolic rate and make long-term weight maintenance more difficult

The lethal dose in humans would be approximately 21,000mg for a 70kg person, making the 1-3mg daily doses used in typical protocols extremely safe from a toxicity standpoint

[1] Cell Line:Cultured Sprague-Dawley rat Achilles tendon fibroblasts (passages 2-4) Concentration:0, 0.5, 1, 2 g/mL Incubation Time:24 h Result:Did not alter total FAK, paxillin, or PCNA protein levels

However, sermorelin is preferred over recombinant growth hormone as it causes fewer side effects