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Moreover, advanced light-dark schedules in genetically predisposed mice (e.g., K-ras/p53 mutants) led to enhanced tumor growth and cell proliferation with increased oncogene c-Myc expression, while clock gene knockouts have tumor suppressive effects 203
Conclusion PROM developers consider it feasible to involve children younger than 8-years-old in the qualitative development of PROMs in QoL research
The attenuated cytoplasmic processes merge with the background stroma (Figure 5)
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