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The absorption of glutathione and other substances from the gastrointestinal tract 38 and oral mucosa 39 has been the subject of some studies and it is now well known that orally administered glutathione cannot be relied upon for therapeutic purposes
Two years later, work from the Bronx VA Medical Center described exendin-4, a molecule that resembled human GLP-1 but lasted far longer in circulation
Despite their overall safety profile, older adults taking GLP-1s who have frailty or a history of heart attack or stroke may need additional clinical support to ensure that they are meeting their nutritional needs and getting sufficient physical activity to mitigate reductions in muscle mass and function
Additionally, by improving insulin sensitivity and blood sugar regulation, GLP-1 medications help address the metabolic changes that may contribute to abdominal weight gain
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