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While that may sound destabilizing, it points to a conformational shift in DNA duplex architecture that could facilitate transcription while preventing hardening of the genome that often accompanies age and oxidative stress [37]
"Concerning BPC-157, a natural pentadecapeptide, that acts as a cytoprotectant and is believed to protect the gastro-intestinal tract (GIT)"
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Research note: A 2025 literature and patent review catalogued BPC-157's multifunctional activity across gastrointestinal, musculoskeletal, neurological, and cardiovascular preclinical models
144 However, there are some anti-HIV drugs that do enter the CNS in significant amounts
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