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The most frequently reported adverse effects are gastrointestinal in nature and typically occur during treatment initiation or dose escalation

Although the risk appears to be extremely low, it serves as a reminder that all medications carry both benefits and risks

We reasoned that replacing the T7 RNAP-transcribed gIII cassette with a chloramphenicol resistance gene would enable the selective enrichment of bacterial cells that express substrates cleaved by a protease of interest when challenged with antibiotic (Fig