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Prophylactic mastectomy is recommended for some people with genetic mutations that significantly raise the lifetime risk of breast cancer

Hjberg PV, Vilsbll T, Rabl R, et al

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Although oxidative stress, mitochondrial damage, and cell death involved in the pathogenesis of APAP hepatotoxicity have been reported [25], accumulating studies on the pathogenesis of APAP hepatotoxicity indicate that subsequent inflammatory responses of the immune system critically determine the severity and outcome of disease [26, 27]

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