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Tirzepatide 5 mg showed an average weight loss of more than 5% of body weight at the median time of 16 weeks, while 10 and 15 mg took 12.4 weeks to show significant weight changes and glycemic control
During the train phase, the animal was placed in a corner quadrant and allowed freely explore the apparatus for 5 min to promote habituation to the experimental environment
showed that mutations in HspB1 reduce its thermal stability, making it more susceptible to denaturation and aggregation (Muranova et al., 2020)
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