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In its main 56-week clinical trial, patients on the highest dose lost an average of 8 percent of their starting body weight

Regardless, constipation can contribute to UTIs, and it is well known that both GLP-1 and GLP-1/GIPs, such as tirzepatide, cause decreased GI motility as one of the ways they assist in weight reduction

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Standard protocols use 1-4mg daily, representing a margin of safety exceeding 5,000-fold

Now, peptide sprays are also emerging as a fast-growing category, with brands like Drift helping lead the way