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Finally, agonist-induced internalization and recycling of a green fluorescent protein (GFP)-tagged human GLP-1R construct expressed in HEK 293 cells was visualized using confocal microscopy (Fig

Research has highlighted its effects on body weight, glucose metabolism, hepatic fat reduction, and energy expenditure, with the glucagon component adding a thermogenic dimension that distinguishes it from earlier single- and dual-agonist compounds